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FOXO1 transgenic mice have a lower skeletal muscle mass than non-transgenic mice [57]

Computer simulation of heterogeneous single nucleotide polymorphisms in the catalase gene indicates structural changes in the enzyme active site, NADPH-binding and tetramerization domains: a genetic predisposition for an altered catalase in patients with vitiligo

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This pattern indicates strong purifying selection during tumor progressioninitially permissive of moderate-mutant level but ultimately favoring metabolic efficiency in advanced stages

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