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Rat inferior caval vein (ICV) ligature and particular pentadecapeptide BPC 157 action

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However, given the retrospective design of the present study, these observations should be interpreted with caution and require validation in larger, prospective or longitudinal studies before any clinical utility can be established

In MIR/I rats, Rb3 increased total antioxidant levels, induced PERK phosphorylation and nuclear translocation of transcription factor Nrf2, and promoted the expression of antioxidant genes such as HMOX1, thereby reducing the size of myocardial infarction (Sun et al., 2019)

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Such modulation influences various biochemical processes essential for health and disease prevention