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Vitamin C is required for hydroxylation of proline and lysine the critical step in collagen triple helix formation (Pullar, Carr and Vissers, 2017)

doi: 10.1042/BJ20110162 123 KuznetsovAVMargreiterR

These include: Vegans or strict vegetarians People whove had surgery for weight loss or stomach cancer People with pernicious anemia People older than 50 Food

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Metagenomic sequencing of the mouse gut microbiota and enzyme-linked immunosorbent assay were used to evaluate whether formononetin reduced TMAO production by modulating gut microbiota