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doi: 10.3389/fendo.2024.1445878 Received 08 June 2024 Accepted 19 November 2024 Published 04 December 2024 Volume 15 - 2024 Edited by Roberto Fernandes da Costa, Autonomous University of Chile, Chile Reviewed by Ying Lu, Shenzhen Second Peoples Hospital, China Xin Sun, The First Affiliated Hospital of Soochow University, China Updates Copyright 2024 Peng, Wang, Gu, Wang, Teng and Shan

Gootenberg J.S., Abudayyeh O.O., Lee J.W., Essletzbichler P., Dy A.J., Joung J., Verdine V., Donghia N., Daringer N.M., Freije C.A., Myhrvold C., Bhattacharyya R.P., Livny J., Regev A., Koonin E.V., Hung D.T., Sabeti P.C., Collins J.J., Zhang F

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ATG9, a transmembrane protein found in vesicles that originate from the trans-Golgi, endosomes or even the plasma membrane, is recruited to the PAS together with ULK1 and has been implicated as a seed for the initial establishment of membrane contact sites in yeast (52) and mammals (53, 54) ( Figure 1 , panel 2)