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I need to see large-scale human trials showing safety and efficacy

We observed that n-acetylglutamic acid (arginine precursor) was enriched in T2, whereas cytosine, xanthine, and 7-methylguanine (nucleotide metabolism), together with threosphingosine and 3-methylxanthine (active metabolites) where enriched in T3, whilst hydrocinnamic acid (active metabolite) was depleted

I will read again and mull over and I will find the link and post the article my daughter read