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Based on this, NSC185058, an ATG4B inhibitor, can greatly enhance the effect of radiotherapy in GBM clinical treatment [123]

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Analysis of RCC cancer patient data in cBioPortal, using the PanCancer Atlas dataset, reveals the overexpression of ser/gly pathway enzymes in a subset of patients with poor outcome, indicating that RCC cancers are also characterized by ser/gly synthesis dependency (Figure S10)

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