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Description

Therapeutic Strategies for Alzheimer's Disease Alzheimer's disease (AD) remains one of the most challenging neurodegenerative disorders to treat, with no cure currently available

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Immunohistochemistry Immunohistochemical staining was performed on paraffin sections prepared from xenograft or PDX tumor tissues

Age showed weak correlation with LAVi, IVSD, and LVEF (R= 0.19, 0.18, 0.16, respectively, p 238 dB/m without viral hepatitis coinfection or alcohol abuse

The results highlight the possibility that Pin1 functions as a molecular timer that finetunes PKC phosphorylation and activation and contributes to the regulation of its downstream effector molecules