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IKKbeta-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier

Second, informative injury models need to mimic the injuries seen in sporting environments (Wall and Shani, 2008), yet most brain injury models create focal hemorrhagic cortical lesions caused by direct impact to the skull or exposed brain (Xiong et al., 2013), while the human concussed brain is more commonly associated with distributed white matter alterations (Benson et al., 2007

doi: 10.3389/fcimb.2021.609722 53 HanT.HuX.LiK.ZhangD.ZhangY.LiJ.et al

2021;17(7):e1009746

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Potential role of antioxidants during ethanol-induced changes in the fatty acid composition and arachidonic acid metabolites in male Wistar rats