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Male Wistar rats not subjected to ruthenium red toxicity (60 g/kg, IP) but treated with 10 mg/kg (IP) all showed significant increases of up to 166% in complex I and IV activity levels in the liver and brain mitochondria in a time-dependent manner

This guide does not make that assumption

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Thereafter, pigs in the -CG + NAC group were orally administrated with 50 mg (kg BW) 1 NAC for 3 days, while pigs in the other two groups were orally administrated with the same volume of sterile saline

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Glutathione transferase (GST) forms a second phase of detoxification, catalyzing deactivation of a number of harmful compounds, requiring reduced glutathione as a cofactor, which is irreversibly consumed during GSH conjugation