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Future optimization primarily includes the standardization of FMT procedures, such as donor screening and management, fecal preparation and storage, and the determination of administration routes and doses [425, 433]

Discussion This study builds on our recent discovery that parkin functions as an antioxidant molecule that can neutralize reactive oxygen- and electrophilic species (ROS

The cellular anti-inflammatory action of the nanosheets is achieved by scavenging intracellular ROS of M1 macrophages and promoting their transition to M2 phenotype, which largely prevents mBMSC apoptosis, while the Zn 2+ released from the degrading nanosheets upregulates the ALP level of mBMSCs, facilitating osteogenic differentiation and biomineralization

D.JamesR

10.1016/s0168-8278(01)00037-x J Hepatol

Since B vitamins are water-soluble and excreted through urine, accumulation is minimal even with higher frequencies