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It is different and more severe than the SNPs in other glutathione-related genes discussed above

Redox Sig

Individuals with AEA usually have moderate to severe persistent asthma and often require treatment with high-dose inhaled corticosteroids and even systemic corticosteroids in some instances[2, 5]

Islam et al., 2021

In this review, the authors also demonstrated that only intact schistosome-derived P28GST was able to induce a significant reduction of the clinical score, in contrast to heat-inactivated P28GST that loses its enzymatic activity (85)

Tregs express more PD-1 than effector T cells in highly glycolytic malignancies, such as MYC-amplified tumors and liver cancers