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IRP2 has also been shown to sense Fe-S cluster levels regardless of its degradation 138 , through a yet-unclear mechanism

Further monitoring of the cancer cells for an additional 10 h demonstrated the gradual decrease of the red fluorescence signal, indicative of the degradation of the nanoparticles inside the cancer cells (Supplementary Fig

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10.1016/j.abb.2007.04.024

GS indicates Glu-Cys ligase catalytic subunit) (Szalai et al

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