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Finally, several small molecules with moderate activity were obtained in the screening, including several derivatives of naphtoquinones, which are also inhibitors of the NF-B pathway (Supplementary Table 4)

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[DOI] [PMC free article] [PubMed] [Google Scholar] [16].Handy DE, Lubos E, Yang Y, Galbraith JD, Kelly N, Zhang YY, Leopold JA, Loscalzo J, Glutathione peroxidase-1 regulates mitochondrial function to modulate redox-dependent cellular responses

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Some of these cellular health processes include DNA repair, breakdown of fatty acids, and inflammatory responses