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IC 50 s of the different inhibitors are reported

Both intracellular and extracellular growth factors can play a significant role in the development of MDR in cancer cells [11, 61, 62]

The staff documents say no

The involvement of oxidative stress mechanisms have also been suggested in some psychiatric illnesses, including depression, anxiety disorders, schizophrenia, and autism spectrum disorders (Valko et al., 2007