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Some observational research has also suggested a slight increase in lung cancer risk linked to long-term, high-dose B6 and B12 supplementation, particularly among men and smokers, although this kind of study cannot prove that the supplements caused the cancers

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World Health Organization

But clearly I think what the study showed was that this is a practice that's probably happening more often in Ontario than it should be happening." Silverstein, a recent graduate of medical school, remembered that little time was spent on the appropriate treatment of B12 deficiency

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