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Collectively, the data presented in this review suggest that an in-depth understanding of the signaling pathways and mechanisms involved in exercises benefits for cardiovascular health will promote the identification and guide the development of novel therapeutic targets and strategies to combat CVD in the future

indeed, low albumin and recent weight loss are strong predictors of poor postoperative outcomes in the elderly [157]

There, Nrf2 binds to antioxidant response elements (ARE) located in the promoter regions of target genes, initiating the transcription of cytoprotective genes and subsequently upregulating the expression of HO-1 and superoxide dismutase 1 (SOD1)

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