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GSH-regulated tumor cell pyroptosis and mechanism study Since Fer-1 (a ferroptosis inhibitor) failed to alleviate the cytotoxicity of NSBSO against B16 cells, we further investigated the mechanism of the rapid and intense death of B16 cells induced by NSBSO

This impairment occurs through the reduction of insulin-stimulated tyrosine phosphorylation of the insulin receptor and IRS-1, an increase in serine phosphorylation of IRS-1, and, hence, inhibition of Akt phosphorylation

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Journal of Neurotrauma 33 (12): 11281135

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For patients seeking visible skin improvement, injectable glutathione remains the preferred choice