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Whether a cell undergoes ferroptosis is largely determined by intertwined signals from subcellular organelles such as mitochondria, lysosomes, and peroxisomes, which coordinately regulate ROS production as well as lipid oxidation in the process of ferroptosis [46]

doi: 10.1158/0008-5472.Can-14-3804 86 WangLFangBFujiwaraTKragerKGorantlaALiCet al

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Thus, we naturally extended our analysis to other glioma datasets, and in all of them, we consistently found that overexpression of GPX7 was associated with a worse prognosis (Supplementary Fig