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doi: 10.1038/s41577-019-0203-y 206 WikJASklheggBS

For example, functionalizing Lactobacillus rhamnosus GG with ROS-responsive nanomicelles enables targeted delivery of 18-glycyrrhetinic acid at inflamed sites, thereby scavenging excess ROS and repairing the epithelial barrier (Zhang X

found that 4 could bind to IKK through the covalently binding of Cys179 in IKK [126]

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First, mechanistic work should integrate spatial metabolomics and mitochondrial proteomics to map ferroptosis pathways in cerebellar, spinal, and cardiac tissues from FRDA patients, with emphasis on the interaction between the ironsulfur cluster synthesis complex (NFS1ISCUISD11) and ferroptosis-related molecules (GPX4, Nrf2)

10) indicate a complex interaction between NFT derivatives and the Nrf2 pathway