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System X c , the most up-stream node in the ferroptosis signaling cascade (Sato et al., 2018

2.14 Kunming mice insights into Alzheimers disease research Kunming mice, closely related to the C57BL strain, are highly valued in AD research for their resilience, adaptability, and high reproductive efficiency

Although other types necrotic cell death such as pyroptosis and necroptosis are mediated by the formation of membrane pore, ferroptosis is believed to result from the accumulation of unrepaired cell damage [70]