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Recent findings have hinted that any abnormality in these two opposing processes can influence the quantity and quality of mitochondria, which will further affect mitochondrial function and the ability of cells to adjust their mitochondrial networks in response to physiological adaptations and stress conditions (Palikaras et al., 2015

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Am J Med Genet B Neuropsychiatr Genet 141B:947956 Cadenas E, Davies KJ (2000) Mitochondrial free radical generation, oxidative stress, and aging