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[DOI] [PubMed] [Google Scholar] 134.Pastore A., Federici G., Bertini E., Piemonte F

Erythrocytes and the transport of drugs and endogenous compounds

(2015) 10:e0120203

Braz J Med Biol Res 40(3):285

There has been extensive preclinical in vitro and in vivo research showing the relationship between metals such as copper, zinc, and iron and the onset and progression of neurodegenerative conditions such as Alzheimers disease

Clinically, FRDA is a progressive disease characterized by ataxia, areflexia, speech disturbance (dysarthria), sensory loss, motor dysfunction, cardiomyopathy, diabetes, and scoliosis (77)