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In many other organisms, PPDK is a critical enzyme

Reconstituted BPC-157 can be frozen, but freeze-thaw cycles significantly accelerate degradation

Scar tissue can be formed in the pancreas, causing loss of function

In contrast, in situ cancer vaccines leverage the entire tumor antigen repertoire from the outset, enabling rapid, broad, and dynamically expanding polyclonal T-cell responses, whereas personalized vaccines deliver delayed but precisely targeted responses against selected neoantigens