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Similarly, this is seen in supporting thyroid function and reducing muscle fatigue and oxidative damage, enabling more effective workouts

doi: 10.1038/mi.2011.30 [DOI] [PMC free article] [PubMed] [Google Scholar] 45

Consistent with these findings, in vivo experiments revealed a significant reduction in Sirt1 protein expression in the livers of mice upon NNMT knockdown