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Sitting for long hours, bending and driving in a car increases the pressure on the herniated disc, which in turns increases the compression of your sciatic nerve

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Heels may not move into a normal varus position when standing on toes

doi: 10.1146/annurev.nutr.19.1.217 18

Another concept is to measure B12 bound to the plasma protein transcobalamin (holoTC, active B12) before and after administration of three high physiological doses of B12 for two days

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