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Specifically, the accumulation of misfolded CFTR in the endoplasmic reticulum (ER), as in the case of the F508del mutation, induces ER stress that fuels ROS production

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We have shown that is difficult to explain PQ toxicity towards SH-SY5Y cells by apoptosis, necroptosis, or ferroptosis (Hirayama et al., 2018)

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IV delivery allows for achieving optimal serum levels that might be difficult to reach with oral forms

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R., Radwan, P., Radwan, M., Barcz, E., Poski, R., Motak-Pochrzst, H., Banasik, M., Sobczyski, M., & Kunierczyk, P

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Access this article Similar content being viewed by others References Bar-Peled M, Raikhel NV (1996) A method for isolation and purification of specific antibodies to a protein fused to the GST

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