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AdamsKFFelkerGMFraijGPattersonJHOConnorCM

Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required Mol Cell Biol 1996 16 : 60376045 Abu-Amer Y, Dowdy SF, Ross FP, Clohisy JC, Teitelbaum SL

Whilst there is experimental evidence for a variety of novel roles for NAC, further clinical studies are required before it can be recommended for the routine management of any disorders other than that of paracetamol poisoning