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Compounded medications are not reviewed or verified by the FDA for safety, effectiveness, or quality and are not FDA-approved

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10.13345/j.cjb.220724 39 MahmudM

Nitrofurantoin is a prodrug that is activated by cellular nitroreductases leading to the formation of reactive species that damage cellular macromolecules, most prominently DNA, causing nucleoid relaxation and, at high doses, destruction of the entire nucleoid

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We also rate the evidence for safety of long-term N-acetylcysteine use