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Parkinsons disease and gut microbiota: from clinical to mechanistic and therapeutic studies

Cui X, Mi T, Xiao X, et al

With the exception of APC2, each cullin is thought to assemble into a ligase with a similar architecture, where the amino terminus of the cullin engages targets and functions as a substrate targeting module, and the carboxy terminus engages the E2, functioning as a ubiquitin transfer module (Figure 1B)

Dihexa represents a new frontier in how we support brain health across the lifespan

Suppressing it too aggressively with anti-inflammatory medications can actually impair healing

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