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So far, six patients with clEDS and tissue fragility have been reported in the literature, predominantly but not exclusively of the gastrointestinal tract: (1) perforation of colonic diverticulum, development of multiple abscesses requiring partial colectomy, complicated by second small bowel perforation in a 36-year-old man

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Possible biotin deficiency in adults receiving long-term total parenteral nutrition

Thymulin is an essential hormone for T lymphocyte differentiation and the normalization of T-helper cells to suppressor cells