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Synthesis (1) 156g (1mol) of whey acid was dissolved in 2000mL of water, warmed up to 80, and then added 1.2mol of ammonia with a mass percentage concentration of 25% with stirring, and the reaction time was 1.5 hours at the above temperature, after the reaction was completed, concentrated, cooled down, analyzed the crystals, and filtered to obtain ammonium salt of orotate

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Additionally, 1030% of patients of those who are resistant to the effects of antidepressants and thus non-responders to treatment

Using patch clamp electrophysiology, the researchers showed that curcumin potentiated 7-nAChRs in rat hippocampal neurons, and also restored SOD and CAT activity interactions (Jayaprakash et al., 2021)

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