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The latter is referred to as the senesence associated secretory phenotype (SASP) and this is considered to be driving many aspects of functional decline

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Recent investigations have focused more on combination therapies, particularly pairing glutathione with its precursors (l-cystine, cysteine peptides) or other antioxidants (vitamin C, alpha-lipoic acid, zinc), reflecting the understanding that synergistic effects may enhance skin-lightening outcomes

This results in a reduced appearance of fine lines and improved overall skin texture

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Such responses usually resolve within the first two weeks