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Other neurodegenerative conditions affecting the basal ganglia dont show this deficiency

In non-obese diabetic (NOD) strain, supplementation of microbial metabolites acetate and butyrate provided protection against type 1 diabetes by enhancing gut integrity, decreasing diabetogenic cytokines, inhibiting autoreactive T cell, and inducing Treg functions (116)

There was no significant difference between the two groups in terms of BMI, testosterone levels, or oestradiol levels (94)

Early reports suggest its well-tolerated, but long-term safety is still being evaluated

doi: 10.1016/j.vph.2015.03.005 48 InoueKSakanoNOginoKSatoYWangDHKuboMet al

Spread of -synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis