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(When it is fighting off an infection, the body will devote about 25% of its total energy expenditure to the immune system.) The Study This study did something fairly simple: it assessed both mitochondrial activity and oxidative stress in immune cells (PBMCs) in 16 healthy controls, 15 ME/CFS and 15 LC donors

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Peroxidation of fatty acyl groups occurs mostly in membrane phospholipids

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TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum