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"Risk of allodynia with GLP-1 agonists." medRxiv 2026 (preprint) - adjusted HR 2.15 (1.57-2.96) vs bupropion-naltrexone

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[DOI] Kaptan S

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Administered as a once-weekly subcutaneous injection, tirzepatide is available in doses ranging from 2.5 mg to 15 mg, with recommended dose escalation in 2.5 mg increments approximately every 4 weeks to minimize gastrointestinal side effects

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