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Med Sci Sports Exerc 2004

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Neurobiol Aging 11: 169173, 1990

Four weeks of Pycnogenol intake led to a reduction of symptom severity by 20%, whereas it was reduced by 4.5% in placebo subjects

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5-Amino-1MQ reduces NNMT, improving fat function, inflammation, mitochondrial output, and muscle repair.[23][32] In adipocytes, it boosts NAD+ by preventing its wasteful methylation, leading to better glucose handling