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152 Preclinical studies have suggested that cytokine-driven glial activation may contribute to memory impairment and cognitive decline

However, NAC increases intracellular level and bioavailability of Glutathione

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Notably, many patients with CT-detected mucus plugs are asymptomatic yet have worse outcomes, underscoring the importance of mucus as a distinct, mechanism-based therapeutic target rather than merely a symptomatic one [10]

Mediation analysis further indicated that the impact of Akkermansia on cognitive function in late-life depression (LLD) is mediated by FFA (170)

Int Immunopharmacol 158:114825 Aimaiti M, Wumaier A, Aisa Y, Zhang Y, Xirepu X, Aibaidula Y, Lei X, Chen Q, Feng X, Mi N (2021) Acteoside exerts neuroprotection effects in the model of Parkinsons disease via inducing autophagy: network pharmacology and experimental study