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Peer review Peer review information Nature Communications thanks Toni Giorgino and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

The findings of this study allowed the research team of Lau et al to conclude that treatment with cagrilintide in doses ranging from 0.3-4.5 mg resulted in significant dose-dependent weight loss

Functionally, cagrilintide activates amylin receptors AMY1R, AMY2R, AMY3R and the calcitonin receptor (CTR), binding via a conserved bypass motif involving mid-segment residues (S19 P25) (Cao et al

Final Word BPC-157 may well prove to be one of the most important tools in sports medicine and regenerative care