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Natural small molecules regulating the mitophagy pathway counteract the pathogenesis of diabetes and chronic complications

Release 348 , 206238 (2022)

Skyline software (v24.1) 41 was utilized to identify and qualify the metabolites for each sample, using the following parameters: Mass: Monoisotopic peaks, Mass Tolerance: 0.6 Da, Mass Range: 501500 Da. Subsequently, probabilistic quotient normalization and quality control-robust spline signal correction based on QC samples were applied to the metabolomic profile using the metaX R package (v1.4.2)

Briefly, 0.1 g leaves were ground in 3 mL 0.05 mol L 1 phosphate buffer (pH 7.8), and then they were centrifuged at 5000 rpm for 3 min at 4 C

Al-Jamaan, F.R

Hepatology 2015, 62: 635-643