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Finally, to validate ternary complex formation, we transfected NCI-H23 cells with either an empty vector or HA-FBXO28 plasmid, followed by treatment with DJX-A-KM (40 nM) and MG132 (4 M), and performed immunoprecipitation assays

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Beyond these costs are the hardships and sacrifices suffered by family members and other caregivers, accompanied by the frustration experienced by health care professionals as patient cognitive abilities slowly decline