clinicaltrials gov ghk cu GHK-Cu Copper Tripeptide-1 Order Research Grade GHK-CU -

The peptide sits on the skins surface

Kohno, T

PDRN also inhibits microphthalmia-associated transcription factor (MITF), which reduces melanin synthesis

It is a progressive biological renovation better hydration in the first two weeks, visible texture refinement by weeks 34, measurable firming and wrinkle reduction by weeks 812, and a genuinely younger-looking dermis by week 20

This peptide is the active ingredient in the topical copper peptides that have been sold as cosmetic agents on the dermatology shelf since the late 1980s, with the caveat being that topical GHK-Cu needs to penetrate the stratum corneum layer of skin before getting to the dermis, which houses the receptors for the peptide

Alpha and beta hydroxy acids Exfoliating acids like glycolic acid, salicylic acid, and lactic acid can interfere with copper peptide efficacy