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The extended half-life of approximately 7 days is due to albumin binding and resistance to DPP-4 degradation, enabling convenient once-weekly dosing [1]

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This segment of the REZ, measuring 22.5 mm, is particularly susceptible to damage secondary to extrinsic compression (vascular loop, meningioma, etc).5 Local nerve compression at the transition zone induces focal demyelination of proprioceptive fibres, which transmit tactile stimuli from the skin or mucosa of the face, promoting contact between exposed axons and the unmyelinated axons of the nociceptive fibres

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