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The TM1 stalk (135-138) of CTR in the Cagri CT-like conformation also undergoes rearrangement relative to the bypass conformation, in which the phenyl of F137 1.28 packs against F15 Cagri , H18 Cagri and S19 Cagri (Fig

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Detection of alpha-hydroxyethyl free radical adducts in the pancreas after chronic exposure to alcohol in the rat

If these differences in rates apply when the study was carried out, this would imply that the expected number of deaths would have been inflated by about 14% (and the rate ratio underestimated by that amount)