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[DOI] [PMC free article] [PubMed] [Google Scholar] 15.Hayes J.D., Pulford D.J., Ellis E.M., McLeod R., James R.F., Seidegard J., Mosialou E., Jernstrom B., Neal G.E

These preliminary studies suggest a potential therapeutic effect of oral administration of GSH in NAFLD

However, due to the complexity of its pathogenesis, there are no effective treatment measures in clinical settings, which has caused HS to become a high-mortality disease

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A preclinical study showed that NAC (1 mM and 24 h) lowered mitochondrial ROS production, returned MTT reduction rate to control levels, and also increased ATP levels in human neuroblastoma SH-SY5Y cell lines carrying G93A SOD1 mutation [155]