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While these hubs are embedded in specific anatomical locations, they have functional roles across a wide range of tasks

Acetate can contribute to ennvironment acidification and this is an appreciated feature since LAB can compete with other less acidophylic organisms (most pathogenic bacterial species) present in the same ecosystem

Kim JY, Son MJ, Son CY, Radua J, Eisenhut M, Gressier F, et al

Rooney et al., 2020)

Whereas, during OGD, only a high dose of L-lactate at 20 mM is the capacity of reversing the ATP decline to prevent cell death in primary cultured neurons and N2A cells, but not the low dose at 1 mM (13)

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