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Acknowledgments We thank Dr Pingzhao Zhang for providing us critical advice

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Omega-3 supplementation seems to be an option that can be effective in improving the lipid profile and reducing cardiovascular risk, as metabolic nuclear receptors like PPAR and SREBP-1 (sterol regulatory element-binding protein 1) are activated by the binding of natural lipid-derived ligands such as fatty acids, allowing the inhibition of protein-coding that stimulates lipid synthesis and genes that increase lipid oxidation in the liver and muscle

The table below summarizes the key distinctions: Benefits Comparison: Which Works Better for Specific Goals