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Q.ZhangY.HoonM

378 Chen et al

These mechanisms are caused by excessive production of ROS by mitochondria (Bhattacharya et al., 2016) and oxidative stress stimulation

Activating just one produces a moderate growth-hormone pulse

These cells are often on the "front lines," where oxidative stress is highest

356 Since Tau can bind and stabilize actin, when Tau expression was increased, the over-stabilized actin prevented Drp1 from localization to mitochondria, down-regulated mitochondrial fission, lengthened mitochondrial morphology in neurons, and overproduced ROS, which induced neuropathy