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Sufficient sample size: a priori statistical power calculations guide determination of number of animals per group

416 Pharmacological intervention through p38-MAPK signaling pathway inhibition or COX-2 suppression has demonstrated efficacy in restoring monocyte functional competence

Dimethyl fumarate and its metabolite monomethyl fumarate have been shown to attenuate BTZ-induced neuronal synapse injury through a mechanism potentially linked to the Nrf2-mediated antioxidant stress response (Kawashiri et al., 2018)

In conjunction with our proposal, we are revising our regulations at 416.171(a)(2)(iii), (iv), (vi), (vii), and (viii), which establish the annual update to the ASC conversion factor, the 2.0 percentage point reduction for ASCs that fail to meet the standards for reporting ASC quality measures, and the productivity adjustment, to reflect this one year extension

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