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Both are supplied as lyophilized (freeze-dried) powder that is reconstituted with bacteriostatic water before use in the laboratory

At higher concentrations (10100 M), curcumin suppresses EGFR tyrosine kinase activity, blocking downstream phosphoinositide 3-Kinase (PI3K)/AKT survival signaling in melanoma cells (Manica et al., 2023)

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Interestingly, this work resonates with the aforementioned in vitro study demonstrating the protective effect of Set7/9 inhibition in cardiomyocytes subjected to hypoxia-reoxygenation achieved through Nrf2 stabilization and activation of antioxidant genes [97]

albicans strains lacking these pathogenicity mechanisms are less or non-pathogenic towards host cells in vitro 4,5,6,7,8

Research indicates that probiotic strains, by improving gut microbiota, can increase the expression of BDNF in the brain, thereby ameliorating depressive-like behavior (Zhang et al., 2023)