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Visual and olfactory signs of degradation including re-cloudification after clear dissolution, yellow tint, and sulfur smell are legitimate indicators to discard a vial, not rinse and retry

The data observed in each group were tested for normality using the Kolmogorov-Smirnov test and all parameters were not statistically significant which indicate that data are parametric (normally distributed), so the results were expressed as mean SD

N Engl J Med 364:13671368

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[DOI] [PubMed] [Google Scholar] 259.Goncalves-Dias C., Morello J., Correia M.J., Coelho N.R., Antunes A.M.M., Macedo M.P., Monteiro E.C., Soto K., Pereira S.A